Diagnostic spectral imaging of skin and nasal mucosa by RGB laser-based prototype devices

Janis Spigulis; Uldis Rubins; Edgars Kviesis-Kipge; Inga Saknite; Ilze Oshina; Egija Vasilisina; Agate K. Krievina

doi:10.1117/12.3018710

18 June 2024 Diagnostic spectral imaging of skin and nasal mucosa by RGB laser-based prototype devices

Janis Spigulis, Uldis Rubins, Edgars Kviesis-Kipge, Inga Saknite, Ilze Oshina, Egija Vasilisina, Agate K. Krievina

Proceedings Volume 13009, Clinical Biophotonics III; 130090C (2024) https://doi.org/10.1117/12.3018710
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

Spectral imaging – acquisition of images within specific spectral intervals - is a powerful tool for optical diagnostics, able to provide objective data on various clinical parameters, e.g. abnormal content of biomolecules in pathologic tissues. Performance of diagnostics depends on the spectral selectivity of imaging; from this point, ultra-narrowband spectral line imaging appears well-suited for diagnostic applications. Two prototype devices for triple laser line imaging have been developed and tested in laboratory and clinical environments. Large area or whole-body skin spectral imaging device comprises vertically movable high-resolution camera coupled with a specific illumination unit - side-emitting optical fiber spiral that emits simultaneously three laser spectral lines at the wavelengths 450 nm, 520 nm and 628 nm. In the other device, conventional white broadband endoscopic illumination has been replaced by a combined three spectral line white illumination from a low power RGB laser-fiber system attached to the lighting channel of intranasal endoscope. Both prototypes undergo clinical validation; their design details and preliminary test results are reported and discussed.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Janis Spigulis, Uldis Rubins, Edgars Kviesis-Kipge, Inga Saknite, Ilze Oshina, Egija Vasilisina, and Agate K. Krievina "Diagnostic spectral imaging of skin and nasal mucosa by RGB laser-based prototype devices", Proc. SPIE 13009, Clinical Biophotonics III, 130090C (18 June 2024); https://doi.org/10.1117/12.3018710

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