Determination of thermal and physical properties of port-wine stain lesions using pulsed photothermal radiometry

J. Stuart Nelson M.D.; Steven L. Jacques; William H. Wright

doi:10.1117/12.137357

1 June 1992 Determination of thermal and physical properties of port-wine stain lesions using pulsed photothermal radiometry

J. Stuart Nelson M.D., Steven L. Jacques, William H. Wright

Author Affiliations +

Proceedings Volume 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III; (1992) https://doi.org/10.1117/12.137357
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

A method for quantitative characterization of port wine stain (PWS) is presented. Pulsed photothermal radiometry (PPTR) uses a non-invasive infrared radiometry system to measure changes in surface temperature induced by pulsed radiation. When a pulsed laser is used to irradiate a PWS, an initial temperature jump (T-jump) is seen due to the heating of the epidermis as a result of melanin absorption. Subsequently, heat generated in the subsurface blood vessels due to hemoglobin absorption is detected by PPTR as a delayed thermal wave as the heat diffuses toward the skin surface. The time delay and magnitude of the delayed PPTR signal indicate the depth and thickness of the PWS. In this report, we present an initial clinical study of PPTR measurements on PWS patients. Computer simulations of various classes of PWS illustrate how the PPTR signal depends on the concentration of epidermal melanin, and depth and thickness of the PWS. The goal of this research is to provide a means of characterizing PWS before initiating therapy, guiding laser dosimetry, and advising the patient as to the time course and efficacy of the planned protocol.

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J. Stuart Nelson M.D., Steven L. Jacques, and William H. Wright "Determination of thermal and physical properties of port-wine stain lesions using pulsed photothermal radiometry", Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); https://doi.org/10.1117/12.137357

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