Role of temperature dependence of optical properties in laser irradiation of biological tissue

Sohi Rastegar; Beop-Min Kim; Steven L. Jacques

doi:10.1117/12.137464

7 August 1992 Role of temperature dependence of optical properties in laser irradiation of biological tissue

Sohi Rastegar, Beop-Min Kim, Steven L. Jacques

Proceedings Volume 1646, Laser-Tissue Interaction III; (1992) https://doi.org/10.1117/12.137464
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Optical properties of biological tissue can change as a result of thermal denaturation due to temperature rise; a familiar example is whitening observed in cooking egg-white. Changes in optical properties with temperature have been reported in the literature. Temperature rise due to laser irradiation is a function of the optical properties of tissue which themselves are a function of temperature of the tissue. This creates a coupling between light and temperature fields for biological tissue under laser irradiation. The effects of this coupling on the temperature response and light distribution may play an important role in dosimetry consideration for therapeutic as well as diagnostic application of lasers in medicine. In a previous study this problem was addressed in one dimension, for short irradiation exposures, using certain simplifying assumptions. The purpose of this research was to develop a mathematical model for dynamic optical changes with thermal denaturation and a computer program for simulation of these effects for a multi-dimensional geometry.

Citation Download Citation

Sohi Rastegar, Beop-Min Kim, and Steven L. Jacques "Role of temperature dependence of optical properties in laser irradiation of biological tissue", Proc. SPIE 1646, Laser-Tissue Interaction III, (7 August 1992); https://doi.org/10.1117/12.137464

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