Functional imaging of the brain by MRI

D. LeBihan; Charles-Andre Cuenod; J. Robert Turner; P. Jezzard; Valerie Bonnerot; Thomas A. Zeffiro

doi:10.1117/12.151173

27 August 1993 Functional imaging of the brain by MRI

D. LeBihan, Charles-Andre Cuenod, J. Robert Turner, P. Jezzard, Valerie Bonnerot, Thomas A. Zeffiro

Proceedings Volume 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods; (1993) https://doi.org/10.1117/12.151173
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

Recent developments in Magnetic Resonance Imaging (MRI) enabling imaging of hemodynamics and metabolism hold significant promise in the noninvasive evaluation of normal and abnormal brain function. Among several methods, the most successful approach exploits the sensitivity of MRI to changes in the oxygenation status of hemoglobin (oxy/deoxyhemoglobin) in red blood cells related to local variations in blood flow and oxygen consumption in tissues. In cerebral cortex, such variations may be induced by external stimuli or internal cognitive processes. Typically, MRI signal slightly increases when brain is activated due to increase in oxygen supply (blood flow). These studies suggest that MRI may be the method of choice to study mental and cognitive processes underlying the function of the human brain.

Citation Download Citation

D. LeBihan, Charles-Andre Cuenod, J. Robert Turner, P. Jezzard, Valerie Bonnerot, and Thomas A. Zeffiro "Functional imaging of the brain by MRI", Proc. SPIE 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods, (27 August 1993); https://doi.org/10.1117/12.151173

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available