New sensitizers for diagnosis and photodynamic therapy of malignant tissues

Andrei F. Mironov; Andrei N. Kozyrev; Pavel Yu. Perepyolkin

doi:10.1117/12.168652

1 March 1994 New sensitizers for diagnosis and photodynamic therapy of malignant tissues

Andrei F. Mironov, Andrei N. Kozyrev, Pavel Yu. Perepyolkin

Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168652
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

The strategy for chemical transformation of naturally occurring chlorophylls and bacteriochlorophyll (alpha) has been discussed. The influence of the position and the character of the substitutes on the optical properties was studied. Aminoacid derivatives of purpurin 18 and bacteriopurpurin have been synthesized via direct attachment to propionic acid side chain. Biological trials of chlorin p₆ were performed and discussed.

Citation Download Citation

Andrei F. Mironov, Andrei N. Kozyrev, and Pavel Yu. Perepyolkin "New sensitizers for diagnosis and photodynamic therapy of malignant tissues", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); https://doi.org/10.1117/12.168652

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