Fluorescence diagnostic of wound processes

Nikita Yu. Konstantinov; Mikhail M. Terent'ev; Igor V. Rybakovskii

doi:10.1117/12.166814

15 January 1994 Fluorescence diagnostic of wound processes

Nikita Yu. Konstantinov, Mikhail M. Terent'ev, Igor V. Rybakovskii

Proceedings Volume 2081, Optical Biopsy; (1994) https://doi.org/10.1117/12.166814
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

A set for fluorescence detection of laser-induced processes in biological tissues in the spectral range from 200 nm to 1000 nm was applied for fluorescence diagnostics of wound processes. The water-soluble photosensitizer and tumor-making agent--sulphonated aluminum phthalocyanine (AlPcS) were tested for vital decoration of wound processes. The spectral (optical multichannel analyzer) and image (slow-scan CCD camera) detection of wound process were performed. A high efficiency of laser-induced dye-related fluorescence for wound processes detection and monitoring was demonstrated. The distribution of dye between untreated tissues and different wounds, inflammations and experimental tumors is described. The extremely long uptake time (up to 8 weeks) for AlPcS in wounds and inflammations was observed.

Citation Download Citation

Nikita Yu. Konstantinov, Mikhail M. Terent'ev, and Igor V. Rybakovskii "Fluorescence diagnostic of wound processes", Proc. SPIE 2081, Optical Biopsy, (15 January 1994); https://doi.org/10.1117/12.166814

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