Paper
26 May 1994 Angioscopic and angiographic characteristics of de novo and restenotic lesions following successful coronary rotational atherectomy and balloon angioplasty
Youssef G. Chami M.D., Theodore A. Bass M.D., Barbara J. Kircher M.D., Christopher J. White M.D., Suresh P. Jain M.D., Paul S. Gilmore M.D., Donald A. Conetta M.D.
Author Affiliations +
Abstract
We used coronary angiography and angioscopy prior and following balloon angioplasty (PTCA) and high speed rotational atherectomy (PTCRA) in order to 1) Assess morphological and surface luminal characteristics of de novo (DN) and restenotic (RS) lesions, 2) Compare surface luminal characteristics following PTCA and PTCRA. 3) Investigate whether lesion morphology helped predict response to therapy; 39 lesions were studied in 38 patients undergoing elective coronary intervention. Angiographic and angioscopic variables were compared by Pearson Chi-square. Angiography pre-intervention was not different in DN and RS lesion. On post intervention angiography, presence of intimal dissection was significantly higher in the PTCA group (p < 0.001). On preintervention angioscopy smooth white lesions differentiated RS from DN lesions (yellow colored lesion) (p < 0.01) while color difference persisted post intervention; smoothness and absence of plaque fracture were device related as noted in the atherectomy group (p < 0001). No other lesion variables noted prc.4ntervention hipcd dfffcrentiatz DN from RS lesions or predict response to catheter therapy. We conclude: 1) angioscopy is superior to angiography in assessing surface luminal characteristics; 2) smooth white lesions characterized RS lesions pre—intervention and color difference persisted after intervention. 3) surface luminal characteristics were very different following PTCRA vs. PTCA with a) angiographically less intimal dissection and b) angioscopically smoother lumen with less plaque fracture following PTCRA.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Youssef G. Chami M.D., Theodore A. Bass M.D., Barbara J. Kircher M.D., Christopher J. White M.D., Suresh P. Jain M.D., Paul S. Gilmore M.D., and Donald A. Conetta M.D. "Angioscopic and angiographic characteristics of de novo and restenotic lesions following successful coronary rotational atherectomy and balloon angioplasty", Proc. SPIE 2132, Clinical Applications of Modern Imaging Technology II, (26 May 1994); https://doi.org/10.1117/12.176557
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KEYWORDS
Angiography

Remote sensing

Color difference

Health sciences

Cardiac catheterization

Cardiology

Holmium

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