Laser Doppler perfusion monitoring and imaging of blood microcirculation

Gert E. Nilsson; Karin Wardell

doi:10.1117/12.180808

21 July 1994 Laser Doppler perfusion monitoring and imaging of blood microcirculation

Gert E. Nilsson, Karin Wardell

Proceedings Volume 2136, Biochemical Diagnostic Instrumentation; (1994) https://doi.org/10.1117/12.180808
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

Laser Doppler perfusion monitoring is a method of assessing tissue perfusion based on measurements performed using Doppler broadening of monochromatic light scattered in moving blood cells. Ever since laser Doppler perfusion monitors became available about 15 years ago they have been used in numerous applications in both clinical and laboratory settings. The high spatial resolution has in practice manifested itself as one of the main limitations of the method. The reason for this is the difficulty in attaining reproducible values at successive measurement sites because most skin tissue possesses a substantial variation in blood flow even at adjacent measurement sites. In order to overcome this difficulty the laser Doppler perfusion imager was developed. In this camera-like device, the laser beam successively scans the tissue and the Doppler components of the backscattered light are detected by a remote photodiode. After a scanning procedure is complete, a color-coded perfusion map showing the spatial variation of skin blood flow is displayed on a monitor. The operating principle and early applications of this emerging technology are addressed in further detail.

Citation Download Citation

Gert E. Nilsson and Karin Wardell "Laser Doppler perfusion monitoring and imaging of blood microcirculation", Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); https://doi.org/10.1117/12.180808

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