P-31 magnetic resonance spectroscopy and near-infrared spectroscopy provide unique quantitative data for evaluation of exercising muscles

Jane H. Park; Daniel Golwyn; Nancy J. Olsen; John H. Newman; Alvin C. Powers; Beverly C. Davis; Kara Rader; Britton Chance

doi:10.1117/12.186722

14 September 1994 P-31 magnetic resonance spectroscopy and near-infrared spectroscopy provide unique quantitative data for evaluation of exercising muscles

Jane H. Park, Daniel Golwyn, Nancy J. Olsen, John H. Newman, Alvin C. Powers, Beverly C. Davis, Kara Rader, Britton Chance

Author Affiliations +

Proceedings Volume 2275, Advanced Microwave and Millimeter-Wave Detectors; (1994) https://doi.org/10.1117/12.186722
Event: SPIE's 1994 International Symposium on Optics, Imaging, and Instrumentation, 1994, San Diego, CA, United States

Abstract

P-31 magnetic resonance spectroscopy (MRS) and near-infra spectroscopy (NIRS) have been used to characterize the dynamic aspects of human muscle contraction. P-31 MRS is a non- invasive method for measuring ATP, phosphocreatine (PCr), and pH in exercising muscles and thereby provides information regarding oxidative and glycolytic capacities for generating high energy phosphate compounds. NIRS evaluates kinetic changes in oxygen levels in muscles during exercise and recovery. These two methods provide unique quantitative data for studies of normal muscle contraction and for more complex investigations of muscle diseases. Non-invasive MRS and NIRS examinations are readily repeatable and yield important data for longitudinal patient evaluation and therapeutic management.

Citation Download Citation

Jane H. Park, Daniel Golwyn, Nancy J. Olsen, John H. Newman, Alvin C. Powers, Beverly C. Davis, Kara Rader, and Britton Chance "P-31 magnetic resonance spectroscopy and near-infrared spectroscopy provide unique quantitative data for evaluation of exercising muscles", Proc. SPIE 2275, Advanced Microwave and Millimeter-Wave Detectors, (14 September 1994); https://doi.org/10.1117/12.186722

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