Optical analysis of blood in motion distinguishing absorption from multiple scattering

Peter Richard Smith; Gabriela Ruiz de Marquez; Harry Thomason

doi:10.1117/12.198708

4 January 1995 Optical analysis of blood in motion distinguishing absorption from multiple scattering

Peter Richard Smith, Gabriela Ruiz de Marquez, Harry Thomason

Proceedings Volume 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging; (1995) https://doi.org/10.1117/12.198708
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

The absorption and scattering of light through a taut flexible tube containing flowing samples of whole blood and haemolysed blood are studied by high resolution linear imaging of the transmitted intensity. A 16-bit photodiode array is used to obtain transmission profiles which are compared to a theoretical model developed from Twersky's multiple scattering theory. Profiles from near the edge of the vessel cavity are shown to be especially important in classifying the concentration and nature of the suspensions. The distribution of red blood cells across the vessel diameter is shown to be a function of the haematocrit and cell morphology. The measurement technique is relevant to blood vessel physiological studies and noninvasive blood analysis.

Citation Download Citation

Peter Richard Smith, Gabriela Ruiz de Marquez, and Harry Thomason "Optical analysis of blood in motion distinguishing absorption from multiple scattering", Proc. SPIE 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging, (4 January 1995); https://doi.org/10.1117/12.198708

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