Allosteric ATPase behavior: the onset of laser-sustained enzyme cooperation

F. Causa; Michele Costato; Marziale Milani; Lorenzo Bolognani

doi:10.1117/12.197473

2 January 1995 Allosteric ATPase behavior: the onset of laser-sustained enzyme cooperation

F. Causa, Michele Costato, Marziale Milani, Lorenzo Bolognani

Proceedings Volume 2370, 5th International Conference on Laser Applications in Life Sciences; (1995) https://doi.org/10.1117/12.197473
Event: Laser Applications in Life Sciences: 5th International Conference, 1994, Minsk, Belarus

Abstract

A two level model is considered to describe the dynamics of a biological system undergoing cyclic oscillations from one state to another separated by an energy quantum interval. This is typically met in enzyme activated reactions, involving the ADP-ATP cycle. General results can be obtained analytically, the dynamics of the system being investigated from an energetic point of view. Numerical solutions show how an enzymatic system can be driven across different regimes where cooperation (allostericity) and oscillations appears. The model can be extended to the case of an external energy supply in the form of electromagnetic radiation, providing clues for a physical understanding of nonthermal laser interaction with biosystems.

Citation Download Citation

F. Causa, Michele Costato, Marziale Milani, and Lorenzo Bolognani "Allosteric ATPase behavior: the onset of laser-sustained enzyme cooperation", Proc. SPIE 2370, 5th International Conference on Laser Applications in Life Sciences, (2 January 1995); https://doi.org/10.1117/12.197473

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