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The determination of the mean velocity of biological objects provides essential information about different biological systems: (1) motility measurements of microorganisms to test the water quality, (2) motility test of spermatozoa, and (3) blood flow measurements in capillaries. A description of these phenomena in terms of the speckle effect shows the correlation between the spectrum of the time dependence of the speckle pattern and the mean object velocity. No severe assumptions must be made. In the case of blood flow, one can differentiate between the blood flow and a superimposed movement of the surrounding tissue.
Bernhard Ruth
"Dynamic speckle patterns: a tool for determining the mean velocity of biological objects", Proc. SPIE 2732, CIS Selected Papers: Coherence-Domain Methods in Biomedical Optics, (9 February 1996); https://doi.org/10.1117/12.231683
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Bernhard Ruth, "Dynamic speckle patterns: a tool for determining the mean velocity of biological objects," Proc. SPIE 2732, CIS Selected Papers: Coherence-Domain Methods in Biomedical Optics, (9 February 1996); https://doi.org/10.1117/12.231683