Generating subsurface acoustic waves in indocyanine-green-stained elastin biomaterial using a Q-switched laser

John A. Viator; Steven L. Jacques; Scott A. Prahl

doi:10.1117/12.308154

13 May 1998 Generating subsurface acoustic waves in indocyanine-green-stained elastin biomaterial using a Q-switched laser

John A. Viator, Steven L. Jacques, Scott A. Prahl

Author Affiliations +

Proceedings Volume 3254, Laser-Tissue Interaction IX; (1998) https://doi.org/10.1117/12.308154
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

A Q-switched frequency-doubled Nd-YAG laser coupled to an optical parametric oscillator generated 4.75 ns 800 nm laser pulses to create a subsurface acoustic wave in planar indocyanine green gel samples and flat segments of elastin biomaterial stained with indocyanine green. The acoustic waves traveled through the target and were detected by a piezoelectric transducer. The waveforms were converted to measurements of pressure (and temperature) as a function of depth in the material. An algorithm was developed and applied to the acoustic signals to extract information about the absorption coefficient as a function of depth in the samples.

Citation Download Citation

John A. Viator, Steven L. Jacques, and Scott A. Prahl "Generating subsurface acoustic waves in indocyanine-green-stained elastin biomaterial using a Q-switched laser", Proc. SPIE 3254, Laser-Tissue Interaction IX, (13 May 1998); https://doi.org/10.1117/12.308154

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