Real-time optoacoustic monitoring of temperature in tissues

Rinat O. Esenaliev; Alexander A. Oraevsky; Kirill V. Larin; Irina V. Larina; Massoud Motamedi

doi:10.1117/12.350008

14 June 1999 Real-time optoacoustic monitoring of temperature in tissues

Rinat O. Esenaliev, Alexander A. Oraevsky, Kirill V. Larin, Irina V. Larina, Massoud Motamedi

Proceedings Volume 3601, Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical; (1999) https://doi.org/10.1117/12.350008
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

There is a need to monitor tissue temperature and optical properties during thermotherapy in real time in order to control the boundaries of hyperthermia or coagulation of diseased tissues and minimize the damage to surrounding normal tissues. We propose to use optoacoustic technique for monitoring of tissue temperature. Efficiency of thermoacoustic excitation in water is dependent on temperature. Therefore, the optoacoustic technique may be utilized to monitor tissue temperature if the efficiency of thermoacoustic excitation in tissue is temperature-dependent. We performed experiments on real-time optoacoustic monitoring of temperature in freshly excised canine tissues (liver and myocardium) and aqueous solution during conductive heating. Laser-induced optoacoustic pressure signals were recorded from tissues and the aqueous solution during heating with the use of sensitive wide-band acoustic transducers. Fundamental harmonic of Q-switched Nd:YAG lasers were used for pressure wave generation. Amplitude of the optoacoustic pressure induced in tissues increased linearly with temperature. Good agreement was obtained between the experimental data and theory for the aqueous solution. We demonstrated that laser optoacoustic technique is capable of measuring 1 - 2 degrees Celsius temperature change in tissue and at the distance of up to several centimeters between the investigated tissue volume and the transducer.

Citation Download Citation

Rinat O. Esenaliev, Alexander A. Oraevsky, Kirill V. Larin, Irina V. Larina, and Massoud Motamedi "Real-time optoacoustic monitoring of temperature in tissues", Proc. SPIE 3601, Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical, (14 June 1999); https://doi.org/10.1117/12.350008

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available