Color adjustment techniques to improve utility of stereo flicker chronoscopy and chronometry assessment of serial optic disk photographs in glaucoma patients

Robert H. Eikelboom; Kanagasingam Yogesan; Christopher J. Barry; Ludmila Jitskaia; Phillip H. House; William H. Morgan

doi:10.1117/12.348531

21 May 1999 Color adjustment techniques to improve utility of stereo flicker chronoscopy and chronometry assessment of serial optic disk photographs in glaucoma patients

Robert H. Eikelboom, Kanagasingam Yogesan, Christopher J. Barry, Ludmila Jitskaia, Phillip H. House, William H. Morgan

Author Affiliations +

Proceedings Volume 3661, Medical Imaging 1999: Image Processing; (1999) https://doi.org/10.1117/12.348531
Event: Medical Imaging '99, 1999, San Diego, CA, United States

Abstract

The aim of this study was to develop a computerized stereo- flicker chronoscopy and chronometry system to improve the technique of neuroretinal optic disc rim assessment. Digitized stereo photographs of 22 eyes of glaucoma patients were analyzed subjectively by computerized flickering of serial images, and objectively by measuring the width of the neuroretinal rim at 18 positions around the optic disc. A major source of error was identified as color changes in the images over time. Color adjustment algorithms were developed and the assessments and measurements were repeated. For chronometry after color adjustment there was improvement to most of the tests on the data: agreement (50% to 73%), specificity (45% to 84%), positive agreement (50% to 71%) and negative agreement (50% to 73%). Sensitivity remained constant at about 55%.

Citation Download Citation

Robert H. Eikelboom, Kanagasingam Yogesan, Christopher J. Barry, Ludmila Jitskaia, Phillip H. House, and William H. Morgan "Color adjustment techniques to improve utility of stereo flicker chronoscopy and chronometry assessment of serial optic disk photographs in glaucoma patients", Proc. SPIE 3661, Medical Imaging 1999: Image Processing, (21 May 1999); https://doi.org/10.1117/12.348531

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