New supramolecular system binding to nucleic acids

Xue-Mei Wang; Lintao Cai

doi:10.1117/12.364380

17 September 1999 New supramolecular system binding to nucleic acids

Xue-Mei Wang, Lintao Cai

Proceedings Volume 3863, 1999 International Conference on Biomedical Optics; (1999) https://doi.org/10.1117/12.364380
Event: International Symposium on Biomedical Optics, 1999, Wuhan, China

Abstract

The potential of some novel dansylamide derivatives to complex with polynucleotides in aqueous solution has been investigated primarily by absorption, circular dichroism and fluorescence spectroscopy. The results indicate that these spectroscopies are strongly affected upon complexation, which may be contributed to the stacking interactions of the aromatic units, specific electronic interaction, and/or conformational changes of host- guest system. Besides, the nanostructural images of the complexes by atomic force microscopy also provide fresh direct evidence for the relationship between the structures of supramolecules and the relative conformational changes of nucleic acids.

Citation Download Citation

Xue-Mei Wang and Lintao Cai "New supramolecular system binding to nucleic acids", Proc. SPIE 3863, 1999 International Conference on Biomedical Optics, (17 September 1999); https://doi.org/10.1117/12.364380

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