Laser Doppler imaging of myocardial perfusion during coronary bypass surgery

Karin Wardell; Ulf Hermansson; Gert E. Nilsson; Henrik Casimir-Ahn M.D.

doi:10.1117/12.387131

31 May 2000 Laser Doppler imaging of myocardial perfusion during coronary bypass surgery

Karin Wardell, Ulf Hermansson, Gert E. Nilsson, Henrik Casimir-Ahn M.D.

Proceedings Volume 3923, Optical Diagnostics of Biological Fluids V; (2000) https://doi.org/10.1117/12.387131
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

Laser Doppler perfusion imaging has been used to assess the myocardium perfusion on the arrested heart during bypass surgery. Twenty-two patients undergoing coronary artery bypass grafting, including usage of the left internal thoracic artery, were included in the study. The anticipated perfusion increase following declamping of the internal thoracic artery was investigated by mapping areas at the size of 10 cm X 11 cm, (n equals 11) and 7 cm X 5 cm (n equals 11). The larger images allowed quantification of blood flow in different regions of the myocardium. The size of the affected area was 32.2 +/- 12.9 cm² with a total increase of 3.17 +/- 0.75 a.u. (range 0 - 10 a.u.). Corresponding values for areas surrounding the vessels and areas defined as the larger vessels in the myocardium were 29.0 +/- 10.9 cm² (2.85 +/- 0.57 a.u.) and 3.5 +/- 2.8 cm² (6.78 +/- 0.18 a.u.). All subjects but two showed a substantial blood flow increase (> 2 a.u.) after release of the clamp. Six subjects had a total increase of at least 4 a.u. Correlation analysis between areas including various number of sites showed an r equals 0.91 (p < 0,0001) or better. In conclusion, laser Doppler perfusion imaging can easily be used intraoperatively in conjunction with bypass surgery. It enables immediate assessment of both the increase and spatial distribution of myocardial perfusion following declamping of an arterial graft.

Citation Download Citation

Karin Wardell, Ulf Hermansson, Gert E. Nilsson, and Henrik Casimir-Ahn M.D. "Laser Doppler imaging of myocardial perfusion during coronary bypass surgery", Proc. SPIE 3923, Optical Diagnostics of Biological Fluids V, (31 May 2000); https://doi.org/10.1117/12.387131

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