Optical monitoring of tissue viability using reflected spectroscopy in vivo

Avraham Mayevsky; Ari Kraut; Tamar Manor; Judith Sonn; Yehuda Zurovsky

doi:10.1117/12.431553

4 May 2001 Optical monitoring of tissue viability using reflected spectroscopy in vivo

Avraham Mayevsky, Ari Kraut, Tamar Manor, Judith Sonn, Yehuda Zurovsky

Proceedings Volume 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II; (2001) https://doi.org/10.1117/12.431553
Event: Saratov Fall Meeting 2000, 2001, Saratov, Russian Federation

Abstract

Only few techniques that could provide real-time continuous multiparametric physiological data have been developed. Therefore, experimental and clinical monitoring devices for organ and tissue viability evaluation are still lacking. In this study, we present the new concept of tissue vitality defined as a product of a few parameters monitored in real- time by a combined measurement of tissue blood flow and volume as well as the oxidation reduction state of the mitochondria. The hypothesis behind the new approach is that in order to evaluate in real-time tissue vitality, it is necessary to monitor both microcirculatory blood flow and volume as well as the intracellular O₂ balance as reflected in the mitochondrial redox state.

Citation Download Citation

Avraham Mayevsky, Ari Kraut, Tamar Manor, Judith Sonn, and Yehuda Zurovsky "Optical monitoring of tissue viability using reflected spectroscopy in vivo", Proc. SPIE 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, (4 May 2001); https://doi.org/10.1117/12.431553

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