Modified diffusion models for steady-state broadband reflectance with a needlelike optic probe

Hanli Liu; Maureen Johns; Cole A. Giller

doi:10.1117/12.434472

29 June 2001 Modified diffusion models for steady-state broadband reflectance with a needlelike optic probe

Hanli Liu, Maureen Johns, Cole A. Giller

Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434472
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Theoretical models available for optical reflectance with small source-detector separations are limited. In this study we reported two modified diffusion models for steady-state, broadband (500 - 590 nm) reflectance with source-detector separations of 0.125 - 0.25 mm and 0.25 - 1.0 mm. For the former case, the major modifications are D equals 1/3(mu) _s, and z₀ equals 1/(mu) _s'; for the latter case, an additional modification is to multiply the separation by a factor of 2. Monte Carlo simulations were used to confirm the modified models at three different hemoglobin concentrations with relative errors of 12% or smaller. These models provide the possibility to extract local optical and physiological parameters of blood-perfused tissues from reflectance data measured with a needle-like probe.

Citation Download Citation

Hanli Liu, Maureen Johns, and Cole A. Giller "Modified diffusion models for steady-state broadband reflectance with a needlelike optic probe", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434472

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