Simulation study of ultrasound-modulated optical tomography

Gang Yao; Lihong V. Wang

doi:10.1117/12.429307

15 June 2001 Simulation study of ultrasound-modulated optical tomography

Gang Yao, Lihong V. Wang

Proceedings Volume 4256, Biomedical Optoacoustics II; (2001) https://doi.org/10.1117/12.429307
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Monte-Carlo modeling technique was used to simulate the ultrasound-modulated optical tomography. The difference between absorption and scattering objects was compared. Simulation result indicated that this technique is sensitive to object absorption property, while the scattering properties have less effect on the output AC/DC signal intensity. It was also demonstrated that inhomogeneity and the background optical properties of the scattering medium could change the AC/DC value. The signal-to-noise ratio problem in the experiment is carefully analyzed. The major noise source is the speckle noise caused by the small particle movement within the tissue sample. The decorrelation time of the speckle pattern was measured in the tissue sample. In order to reduce the speckle noise, the data acquisition time must be less than the speckle decorrelation time.

Citation Download Citation

Gang Yao and Lihong V. Wang "Simulation study of ultrasound-modulated optical tomography", Proc. SPIE 4256, Biomedical Optoacoustics II, (15 June 2001); https://doi.org/10.1117/12.429307

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