Capillary convection in protein crystal growth

Li Duan; Qi Kang

doi:10.1117/12.449396

26 November 2001 Capillary convection in protein crystal growth

Li Duan, Qi Kang

Proceedings Volume 4448, Optical Diagnostics for Fluids, Solids, and Combustion; (2001) https://doi.org/10.1117/12.449396
Event: International Symposium on Optical Science and Technology, 2001, San Diego, CA, United States

Abstract

An optical diagnostic system consisting of the Mach-Zehnder interferometer with the phase shift device and the image processor has been developed for the study of the kinetics of protein crystal growing process. The concentration capillary convection around growing protein crystal was investigated during the process of trichosanthin crystal growth. The observation in real time showed that the concentration capillary convection associated with the surface tension of the crystallizing solution occurs at the vicinity of the surface of the protein mother liquor and directly affects on the outcome of protein crystallization, including the process of growth and the quality of resulting crystal. So far the detailed analysis and the important role of the concentration capillary convection in protein crystallization has been overlooked in both the space- and the ground-based crystal growth experiments. This may be one of the reasons for the majority of the results of space-based investigation shown no improvement.

Citation Download Citation

Li Duan and Qi Kang "Capillary convection in protein crystal growth", Proc. SPIE 4448, Optical Diagnostics for Fluids, Solids, and Combustion, (26 November 2001); https://doi.org/10.1117/12.449396

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available