Biomodulation of light on cells in laser surgery

Timon Cheng-Yi Liu; Yan Li; Rui Duan; Xiongwei Cai

doi:10.1117/12.462536

12 April 2002 Biomodulation of light on cells in laser surgery

Timon Cheng-Yi Liu, Yan Li, Rui Duan, Xiongwei Cai

Proceedings Volume 4536, International Workshop on Photonics and Imaging in Biology and Medicine; (2002) https://doi.org/10.1117/12.462536
Event: International Workshop on Photonics and Imaging in Biology and Medicine, 2001, Wuhan, China

Abstract

In laser surgery, it has been observed pulsed 532-nm laser can avoid postoperative purpura, but pulsed 585-nm, 595-nm or 600-nm lasers nonetheless cause purpura when they were used to treat port-wine stains; the XeCl excimer laser (308 nm) can safely and effectively clear psoriasis; both XeCl excimer laser and Ho:YAG laser were used in coronary interventions, but only former was approved by the FDA; open channels after ultraviolet (UV) laser treatment and closed channels with infrared (IR) lasers for transmyocardial laser revascularization; and so on. In this paper, the biological information model of low intensity laser (BIML) is extended to include UVA biomodulation and is used to understand these phenomena. Although the central intensity of the laser beam is so intense that it destroys the tissue, the edge intensity is so low that it can induce biomodulation. Our investigation showed that biomodulation of light on cells might play an important role in the long-term effects of laser surgery.

Citation Download Citation

Timon Cheng-Yi Liu, Yan Li, Rui Duan, and Xiongwei Cai "Biomodulation of light on cells in laser surgery", Proc. SPIE 4536, International Workshop on Photonics and Imaging in Biology and Medicine, (12 April 2002); https://doi.org/10.1117/12.462536

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