Dynamic response of ensemble neurons to pulsed optical and electrical excitation in vivo and in vitro

Garif G. Akchurin; George A. Seleverstov; Tatyana G. Kamenskih; George G. Akchurin; Olga A. Bondarenko

doi:10.1117/12.475615

16 July 2002 Dynamic response of ensemble neurons to pulsed optical and electrical excitation in vivo and in vitro

Garif G. Akchurin, George A. Seleverstov, Tatyana G. Kamenskih, George G. Akchurin, Olga A. Bondarenko

Proceedings Volume 4707, Saratov Fall Meeting 2001: Optical Technologies in Biophysics and Medicine III; (2002) https://doi.org/10.1117/12.475615
Event: Saratov Fall Meeting 2001, 2001, Saratov, Russian Federation

Abstract

The nonlinear response of the Hodgkin-Huxley model neuron with external electrical pulsed was investigated. Dynamic response of somatic frog nerve on electrical pulsed duration was study in vitro. Transcutaneous millisecond of excitation of the ganglion cell of the human retina by electric uses is used for diagnosis, determination of the extent of optic nerve damage, and also partial restoration of visual function in patients with glaucoma, myopia and different types of optic nerve atrophy. Correlation between the threshold of phosphen formation and duration of the stimulating electric pulses was determined experimentally in normal eyes and in eyes with various pathologies. Comparison of optical and electrical scintillating frequency gives information about the dynamic processes in the normal and pathological retina.

Citation Download Citation

Garif G. Akchurin, George A. Seleverstov, Tatyana G. Kamenskih, George G. Akchurin, and Olga A. Bondarenko "Dynamic response of ensemble neurons to pulsed optical and electrical excitation in vivo and in vitro", Proc. SPIE 4707, Saratov Fall Meeting 2001: Optical Technologies in Biophysics and Medicine III, (16 July 2002); https://doi.org/10.1117/12.475615

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