Tissue structure analysis at optical immersion

Valery V. Tuchin

doi:10.1117/12.482935

12 September 2002 Tissue structure analysis at optical immersion

Valery V. Tuchin

Proceedings Volume 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment; (2002) https://doi.org/10.1117/12.482935
Event: Photonics Asia, 2002, Shanghai, China

Abstract

This paper presents structural and optical models of tissues with basic multiple scattering, which is transformed to low scattering. It is shown that reflection, transmission, light scattering, and state of polarization of the scattered light by a tissue can be effectively controlled by changes of refractive index of tissue components. Method of matching of the refractive indices of scatterers and ground matter by means of administration of chemical agents is discussed in the framework of control of optical properties of tissues. The possibility of usage of optical immersion method for diagnostic purposes based on contrasting of tumor and other abnormalities, in-depth profiling of tissue and blood, and on monitoring of endogenous and exogenous matter diffusion within tissue is demonstrated.

Citation Download Citation

Valery V. Tuchin "Tissue structure analysis at optical immersion", Proc. SPIE 4916, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, (12 September 2002); https://doi.org/10.1117/12.482935

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