Method to measure the optical properties of small volumes of biological tissues

Fabrizio Martelli; Samuele del Bianco; Giovanni Zaccanti

doi:10.1117/12.478218

29 July 2003 Method to measure the optical properties of small volumes of biological tissues

Fabrizio Martelli, Samuele del Bianco, Giovanni Zaccanti

Proceedings Volume 4955, Optical Tomography and Spectroscopy of Tissue V; (2003) https://doi.org/10.1117/12.478218
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

The method consists in measuring the perturbation provoked by a small volume (0.2-1 ml) of tissue on light propagating through a medium of known optical properties. The absorption and the reduced scattering coefficient of the medium are retrieved from multidistance continuous wave measurements of transmittance. The inversion procedure is based on the solution of the diffusion equation obtained with a perturbative approach. The method has been validated with Monte Carlo results. Experimental results are reported for various kind of tissue. The results obtained shows that the method is particularly effective for low absorbing tissues.

Citation Download Citation

Fabrizio Martelli, Samuele del Bianco, and Giovanni Zaccanti "Method to measure the optical properties of small volumes of biological tissues", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); https://doi.org/10.1117/12.478218

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