Photothermal tweezers

Vladimir P. Zharov; Richard C. Kurten; Jay Bauman

doi:10.1117/12.479832

1 July 2003 Photothermal tweezers

Vladimir P. Zharov, Richard C. Kurten, Jay Bauman

Proceedings Volume 4960, Biomedical Optoacoustics IV; (2003) https://doi.org/10.1117/12.479832
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

This paper presents a new technique for manipulating particles and cells using laser-induced pressure. This technique is based on irradiating absorbing mediums around the particles, creating thermal and pressure gradients. The authors discuss the role of laser-induced bubble formation in manipulating particles. The authors discovered competition from different forces, with each force acting on objects in a different manner - resultant near-field forces push objects away from the laser beam, while far-field forces pull objects toward the beam. During bubble collapse, dynamic suction has a pulling effect that moves the liquid containing the particle toward the beam. The authors use different pulse lasers - CO₂, Ho:YAG, Nd:YAG, and N₂ - to demonstrate the ability of this new technique to manipulate glass microspheres through different optical schemes, including ring geometry of the laser beam and delivery of laser radiation with fibers. The authors also discuss the role of thermal convection in the particle manipulation.

Citation Download Citation

Vladimir P. Zharov, Richard C. Kurten, and Jay Bauman "Photothermal tweezers", Proc. SPIE 4960, Biomedical Optoacoustics IV, (1 July 2003); https://doi.org/10.1117/12.479832

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