Clinical and quantitative assessment of multimodal retinal image fusion

Balaji Raman; Mark P. Wilson; Sheila Coyne Nemeth; Peter Soliz; Enrique Corona

doi:10.1117/12.481384

15 May 2003 Clinical and quantitative assessment of multimodal retinal image fusion

Balaji Raman, Mark P. Wilson, Sheila Coyne Nemeth, Peter Soliz, Enrique Corona

Proceedings Volume 5032, Medical Imaging 2003: Image Processing; (2003) https://doi.org/10.1117/12.481384
Event: Medical Imaging 2003, 2003, San Diego, California, United States

Abstract

The fusion of multi-modal medical images provides a new diagnostic tool with clinical applications. Over the years, image fusion has been used in a number of medical disciplines. However, little fusion work in ophthalmic imaging appears in the literature. With the advent of multi-modal digital information of the retina and advanced image registration programs, the possibility of displaying complementary information in one fused retinal image becomes visually and clinically exciting. The objective of this research was to demonstrate that through fusion of multi-modal retinal information one could increase the information content of retinal pathologies on a fused image. Two aspects of image fusion were addressed in this study: image registration and image fusion of two distinctly different modalities, Fluorescein Angiography (FA) videos and standard color photography. Quantitative analysis of the fusion results was performed using entropy and image noise index. Qualitative analysis was performed by simultaneous visual comparison of two modalities (FA and color) of all registered unfused modes and the fused modes.

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Balaji Raman, Mark P. Wilson, Sheila Coyne Nemeth, Peter Soliz, and Enrique Corona "Clinical and quantitative assessment of multimodal retinal image fusion", Proc. SPIE 5032, Medical Imaging 2003: Image Processing, (15 May 2003); https://doi.org/10.1117/12.481384

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KEYWORDS

Image fusion

Image registration

Image enhancement

Image restoration

Visualization

Wavelets

Angiography

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