Application of in vivo laser scanning microscope in dermatology

Juergen Lademann; H. Richter; N. Otberg; F. Lawrenz; U. Blume-Peytavi; W. Sterry

doi:10.1117/12.518622

13 October 2003 Application of in vivo laser scanning microscope in dermatology

Juergen Lademann, H. Richter, N. Otberg, F. Lawrenz, U. Blume-Peytavi, W. Sterry

Proceedings Volume 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV; (2003) https://doi.org/10.1117/12.518622
Event: Saratov Fall Meeting 2002 Laser Physics and Photonics, Spectroscopy, and Molecular Modeling III; Coherent Optics of Ordered and Random Media III, 2002, Saratov, Russian Federation

Abstract

The state of the art of in-vivo and in-vitro penetration measurements of topically applied substances is described. Only optical techniques represent online measuring methods based on the absorption or scattering properties of the topically applied substances. Laser scanning microscopy (LSM) has become a promising method for investigations in dermatology and skin physiology, after it was possible to analyze the skin surface on any body side in-vivo. In the present paper the application of a dermatological laser scanning microscope for penetration and distribution measurements of topically applied substances is described. The intercellular and follicular penetration pathways were studied.

Citation Download Citation

Juergen Lademann, H. Richter, N. Otberg, F. Lawrenz, U. Blume-Peytavi, and W. Sterry "Application of in vivo laser scanning microscope in dermatology", Proc. SPIE 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV, (13 October 2003); https://doi.org/10.1117/12.518622

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KEYWORDS

Skin

In vivo imaging

Laser scanners

Dermatology

Microscopes

Microscopy

In vitro testing

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