Microendoscopes for imaging of the pancreas

Angelique L. Kano; Andrew R. Rouse; Shona M. Kroto; Arthur F. Gmitro

doi:10.1117/12.529310

1 July 2004 Microendoscopes for imaging of the pancreas

Angelique L. Kano, Andrew R. Rouse, Shona M. Kroto, Arthur F. Gmitro

Proceedings Volume 5318, Advanced Biomedical and Clinical Diagnostic Systems II; (2004) https://doi.org/10.1117/12.529310
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

Patients diagnosed with pancreatic cancer have a 5-year survival rate of only 3%. Endoscopic imaging of the pancreas is limited by the small size of the pancreatic duct, which has an average size of 3 mm. To improve imaging capabilities for the pancreatic duct, two small catheter-based imaging systems have been developed that will fit through the therapeutic channel of a clinical endoscope and into the pancreatic duct. One is a miniature endoscope designed to provide macro-imaging of tissue with both white light reflectance and fluorescence imaging modes. The 1.75 mm diameter catheter consists of separate illumination and imaging channels. At a nominal focal distance of 10 mm, the field of view of the system is ~ 10 mm, and the corresponding in-plane resolution is 60 microns. To complement the broadfield view of the tissue, a confocal microendoscope with 2 micron lateral resolution over a field of view of 450 microns and 25 micron axial resolution has been developed. With an outer diameter of 3 mm, the catheter in this system will also fit through the therapeutic channel and into the pancreatic duct. Images of tissue with both the miniature endoscope and confocal microendoscope are presented.

Citation Download Citation

Angelique L. Kano, Andrew R. Rouse, Shona M. Kroto, and Arthur F. Gmitro "Microendoscopes for imaging of the pancreas", Proc. SPIE 5318, Advanced Biomedical and Clinical Diagnostic Systems II, (1 July 2004); https://doi.org/10.1117/12.529310

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