Ionic current through an open channel: a low-dimensional model of coupling with vibrations of the wall

Rodrigue Tindjong; Alan Applegate; Robert S. Eisenberg; Igor Kaufman; Dimitry G. Luchinsky; Peter V. E. McClintock

doi:10.1117/12.548573

25 May 2004 Ionic current through an open channel: a low-dimensional model of coupling with vibrations of the wall

Rodrigue Tindjong, Alan Applegate, Robert S. Eisenberg, Igor Kaufman, Dimitry G. Luchinsky, Peter V. E. McClintock

Proceedings Volume 5467, Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II; (2004) https://doi.org/10.1117/12.548573
Event: Second International Symposium on Fluctuations and Noise, 2004, Maspalomas, Gran Canaria Island, Spain

Abstract

Ionic motion through an open ion channel is analyzed within the framework of self-consistent Brownian dynamics formalism. A novel conceptual model of coupling of the ion's motion to the vibrations of the pore walls is introduced. The model allows one to include into simulations an important additional mechanism of energy dissipation and the effects of self-induced strong modulation of the channel conductivity.

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Rodrigue Tindjong, Alan Applegate, Robert S. Eisenberg, Igor Kaufman, Dimitry G. Luchinsky, and Peter V. E. McClintock "Ionic current through an open channel: a low-dimensional model of coupling with vibrations of the wall", Proc. SPIE 5467, Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II, (25 May 2004); https://doi.org/10.1117/12.548573

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