Time-domain optical mammography Softscan: initial results on detection and characterization of breast tumors

Xavier Intes; Salim Djeziri; Zahia Ichalalene; Niculae Mincu; Yong Wang; Philippe St.-Jean; Frédéric Lesage; David Hall; David A. Boas; Margaret Polyzos

doi:10.1117/12.593755

9 December 2004 Time-domain optical mammography Softscan: initial results on detection and characterization of breast tumors

Xavier Intes, Salim Djeziri, Zahia Ichalalene, Niculae Mincu, Yong Wang, Philippe St.-Jean, Frédéric Lesage, David Hall, David A. Boas, Margaret Polyzos

Author Affiliations +

Proceedings Volume 5578, Photonics North 2004: Photonic Applications in Astronomy, Biomedicine, Imaging, Materials Processing, and Education; (2004) https://doi.org/10.1117/12.593755
Event: Photonics North, 2004, Ottawa, Ontario, Canada

Abstract

Near-infrared (NIR) technology appears promising as a non-invasive clinical technique for breast cancer screening and diagnosis. The technology capitalizes on the relative transparency of human tissue in this spectral range and its sensitivity to the main components of the breast: water, lipid and hemoglobin. In this work we present initial results obtained using the SoftScan® breast-imaging system developed by ART, Advanced Research Technologies inc., Montreal. This platform consists of a 4-wavelength time-resolved scanning system used to quantify non-invasively the local functional state of breast tissue. The different aspects of the system used to accurately retrieve 3D optical contrast will be presented. Furthermore, preliminary data obtained from a prospective study conducted at The Royal Victoria Hospital of the McGill University Health Center in Montreal will be presented. During this study, 65 volunteers with either abnormal or normal mammograms were enrolled. Analysis of the data gathered by SoftScan demonstrated the potential of the technology in discriminating between healthy and diseased tissue.

Citation Download Citation

Xavier Intes, Salim Djeziri, Zahia Ichalalene, Niculae Mincu, Yong Wang, Philippe St.-Jean, Frédéric Lesage, David Hall, David A. Boas, and Margaret Polyzos "Time-domain optical mammography Softscan: initial results on detection and characterization of breast tumors", Proc. SPIE 5578, Photonics North 2004: Photonic Applications in Astronomy, Biomedicine, Imaging, Materials Processing, and Education, (9 December 2004); https://doi.org/10.1117/12.593755

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