UPT-based biosensor and its application

Yongkai Zhao; Lei Zhou; Huijie Huang; Ruifu Yang; Lihua Huang; Bingqiang Ren; Jian Lu; Xiangzhao Wang

doi:10.1117/12.577006

18 January 2005 UPT-based biosensor and its application

Yongkai Zhao, Lei Zhou, Huijie Huang, Ruifu Yang, Lihua Huang, Bingqiang Ren, Jian Lu, Xiangzhao Wang

Proceedings Volume 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II; (2005) https://doi.org/10.1117/12.577006
Event: Photonics Asia, 2004, Beijing, China

Abstract

An up-converting phosphor technology-based biosensor (UPT-based biosensor) has been developed for immunoassay using Up-converting phosphor (UCP) as the biological marker. The UPT system has realized quantitative detection and has good ability to meet the need of some emergencies. High sensitivity (nanogram/ml), good linear response characteristics and an excellent correlation (R²greater than or equal to 0.95) have been verified by quantitative detection results. The sensitivity of the UPT-based biosensor is better than that of the indirect hemagglutination test in the practical application. All the results are comparable with that obtained by Western Blot detection.

Citation Download Citation

Yongkai Zhao, Lei Zhou, Huijie Huang, Ruifu Yang, Lihua Huang, Bingqiang Ren, Jian Lu, and Xiangzhao Wang "UPT-based biosensor and its application", Proc. SPIE 5630, Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II, (18 January 2005); https://doi.org/10.1117/12.577006

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