Effects of relative humidity on laser light transmittance during cryogen spray cooling of in vitro skin phantoms

Julio C. Ramirez-San-Juan; Bernard Choi; Walfre Franco; John Stuart Nelson; Guillermo Aguilar

doi:10.1117/12.591197

25 April 2005 Effects of relative humidity on laser light transmittance during cryogen spray cooling of in vitro skin phantoms

Julio C. Ramirez-San-Juan, Bernard Choi, Walfre Franco, John Stuart Nelson, Guillermo Aguilar

Author Affiliations +

Proceedings Volume 5686, Photonic Therapeutics and Diagnostics; (2005) https://doi.org/10.1117/12.591197
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

While cryogen spray cooling (CSC) can protect skin epidermis from non-specific thermal damage, spray droplets in-flight and the cryogen/frost layer that forms on the skin surface may pose a potential problem for laser light attenuation due to absorption and/or scattering. Employing a hand piece expressly designed for concurrent light and cryogen delivery on skin phantoms, we studied the effect of relative humidity on light transmittance during and after spray cooling. Cryogen spurts were aimed at a microscope glass slide and a deformable agar phantom preheated at 32°C. According to our results, relative humidity plays a very important role in the light transmission during CSC. Light absorption and/or scattering by the spray droplets in-flight and cryogen/frost layer formation at the surface induced light attenuation values of up to 45%. The higher the relative humidity is, the lower the light transmission.

Citation Download Citation

Julio C. Ramirez-San-Juan, Bernard Choi, Walfre Franco, John Stuart Nelson, and Guillermo Aguilar "Effects of relative humidity on laser light transmittance during cryogen spray cooling of in vitro skin phantoms", Proc. SPIE 5686, Photonic Therapeutics and Diagnostics, (25 April 2005); https://doi.org/10.1117/12.591197

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available