Three-dimensional retinal imaging with ultrahigh resolution, spectral domain optical coherence tomography

Vivek J. Srinivasan; Maciej Wojtkowski; Tony Ko; Mariana Carvalho; James G. Fujimoto; Jay S. Duker M.D.; Joel S. Schuman M.D.; Andrzej Kowalczyk

doi:10.1117/12.591367

18 April 2005 Three-dimensional retinal imaging with ultrahigh resolution, spectral domain optical coherence tomography

Vivek J. Srinivasan, Maciej Wojtkowski, Tony Ko, Mariana Carvalho, James G. Fujimoto, Jay S. Duker M.D., Joel S. Schuman M.D., Andrzej Kowalczyk

Author Affiliations +

Proceedings Volume 5688, Ophthalmic Technologies XV; (2005) https://doi.org/10.1117/12.591367
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

Ultrahigh resolution OCT using broadband light sources achieves improved axial image resolutions of ~2-3 um compared to standard 10 um resolution OCT used in current commercial instruments. High-speed OCT using Fourier/spectral domain detection enables dramatic increases in imaging speeds. 3D OCT retinal imaging is performed in human subjects using high-speed, ultrahigh resolution OCT, and the concept of an OCT fundus image is introduced. Three-dimensional data and high quality cross-sectional images of retinal pathologies are presented. These results show that 3D OCT may be used to improve coverage of the retina, precision of cross-sectional image registration, quality of cross-sectional images, and visualization of subtle changes in retinal topography. 3D OCT imaging and mapping promise to help elucidate the structural changes associated with retinal disease as well as to improve early diagnosis and monitoring of disease progression and response to treatment.

Citation Download Citation

Vivek J. Srinivasan, Maciej Wojtkowski, Tony Ko, Mariana Carvalho, James G. Fujimoto, Jay S. Duker M.D., Joel S. Schuman M.D., and Andrzej Kowalczyk "Three-dimensional retinal imaging with ultrahigh resolution, spectral domain optical coherence tomography", Proc. SPIE 5688, Ophthalmic Technologies XV, (18 April 2005); https://doi.org/10.1117/12.591367

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