CARS microscopy studies of collagen transformation

Georgi I. Petrov; L. Sona; Vladislav I. Shcheslavskiy; Vladislav V. Yakovlev

doi:10.1117/12.591319

30 March 2005 CARS microscopy studies of collagen transformation

Georgi I. Petrov, L. Sona, Vladislav I. Shcheslavskiy, Vladislav V. Yakovlev

Proceedings Volume 5700, Multiphoton Microscopy in the Biomedical Sciences V; (2005) https://doi.org/10.1117/12.591319
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

Nonlinear Raman spectroscopy is employed to study structural transformation of collagen (type I) in solution. Relatively strong signal and polarization background suppression reveal significant changes of the vibrational spectrum of collagen, which are attributed to the formation of cholesteric globules. Circular dichroism spectroscopy confirms the concentration dependent structural transformation. Excellent axial resolution achieved in nonlinear Raman microscopy also allows to study for the first time the effect of large molecule adhesion on the surface.

Citation Download Citation

Georgi I. Petrov, L. Sona, Vladislav I. Shcheslavskiy, and Vladislav V. Yakovlev "CARS microscopy studies of collagen transformation", Proc. SPIE 5700, Multiphoton Microscopy in the Biomedical Sciences V, (30 March 2005); https://doi.org/10.1117/12.591319

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available