Specific biological agent taggants

Johnathan L. Kiel D.V.M.; Eric A. Holwitt; Jill E. Parker; Jeeva Vivekananda; Veronica Franz; Mark A. Sloan; Andrzej W. Miziolek; Frank C. DeLucia Jr.; Chase A. Munson; Yvette D. Mattley

doi:10.1117/12.597640

12 May 2005 Specific biological agent taggants

Johnathan L. Kiel D.V.M., Eric A. Holwitt, Jill E. Parker, Jeeva Vivekananda, Veronica Franz, Mark A. Sloan, Andrzej W. Miziolek, Frank C. DeLucia Jr., Chase A. Munson, Yvette D. Mattley

Author Affiliations +

Proceedings Volume 5795, Chemical and Biological Sensing VI; (2005) https://doi.org/10.1117/12.597640
Event: Defense and Security, 2005, Orlando, Florida, United States

Abstract

The preliminary data presented here suggests that direct coating of biological agent with DNA capture elements and organic semiconductor (DALM) with chelated rare earths such as scandium, europium or neodymium can be used to track the agent, even when the biological components have been subsequently destroyed. The use of these three taggant components in conjunction with each other affords the opportunity to determine the presence of the biological agent by several methods---laser induced plasma spectroscopy, thermochemiluminescence, mass spectroscopy, polymerase chain reaction (PCR; if the primers are left on the DCEs or the agent's own DNA is used as the source of the amplicon). The specific DCE-labeling or PCR allows for confirmation of physical measurement results as specific to the agent.

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Johnathan L. Kiel D.V.M., Eric A. Holwitt, Jill E. Parker, Jeeva Vivekananda, Veronica Franz, Mark A. Sloan, Andrzej W. Miziolek, Frank C. DeLucia Jr., Chase A. Munson, and Yvette D. Mattley "Specific biological agent taggants", Proc. SPIE 5795, Chemical and Biological Sensing VI, (12 May 2005); https://doi.org/10.1117/12.597640

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