Reflectance measurements of skin lesions: noninvasive method for diagnostic evaluation of pigmented neoplasia

E. Borisova; P. Trojanova M.D.; L. Avramov

doi:10.1117/12.633013

7 October 2005 Reflectance measurements of skin lesions: noninvasive method for diagnostic evaluation of pigmented neoplasia

E. Borisova, P. Trojanova M.D., L. Avramov

Author Affiliations +

Proceedings Volume 5862, Diagnostic Optical Spectroscopy in Biomedicine III; 58620A (2005) https://doi.org/10.1117/12.633013
Event: European Conferences on Biomedical Optics 2005, 2005, Munich, Germany

Abstract

The aims of this work are investigation and differentiation between normal skin and pigmented skin lesions by using optical reflectance spectroscopy. Optical reflectance spectra in the wavelength range 400-900 nm were obtained from malignant and benign skin lesions and characteristic differences between them were studied. The lesions were preliminarily classified dermatoscopically (MoleMax II, DERMA Instruments). All suspicious lesions were excised and the materials were investigated histologically by standard methods. An algorithm was developed for differentiation and valuation of the skin tissue condition using dimensionless ratios of the reflectance signal intensities of normal skin and pigmented lesions, which allowed the use of non-normalized reflectance spectra for lesion assessment. These ratios were found to have a definite diagnostic potential, as significant differences were observed between normal skin, benign and malignant pigmented lesions.

Citation Download Citation

E. Borisova, P. Trojanova M.D., and L. Avramov "Reflectance measurements of skin lesions: noninvasive method for diagnostic evaluation of pigmented neoplasia", Proc. SPIE 5862, Diagnostic Optical Spectroscopy in Biomedicine III, 58620A (7 October 2005); https://doi.org/10.1117/12.633013

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available