Double wavelength differential absorption as a technique for early diagnosis of breast cancer

Vladimir V. Liger; Alexander V. Zybin; Kay Niemax; Yuri A. Kuritsyn; Mikhail A. Bolshov

doi:10.1117/12.639949

7 December 2006 Double wavelength differential absorption as a technique for early diagnosis of breast cancer

Vladimir V. Liger, Alexander V. Zybin, Kay Niemax, Yuri A. Kuritsyn, Mikhail A. Bolshov

Proceedings Volume 5973, Current Research on Laser Use in Oncology: 2000-2004; 597304 (2006) https://doi.org/10.1117/12.639949
Event: Current Research on Laser Use in Oncology: 2000-2004, 2004, Moscow, Russian Federation

Abstract

The double-wavelength differential molecular absorption technique with diode lasers is proposed for sensitive detection of functional status of breast tissues. The method is based on the measurement of the transmitted intensity differences of the two beams of diode lasers tuned to selected wavelengths within a broad absorption band of a human breast tissue within 700 - 800 nm spectral range. The strategy for the optimum selection of the diode laser wavelengths and initial adjustment of the detection scheme is developed. The method is demonstrated by the detection of the relative concentrations of two dyes, the optical properties of which are similar to those of a mixture of oxy- and deoxy- hemoglobin. The results of the first clinical tests of the proposed technique are briefly described.

Citation Download Citation

Vladimir V. Liger, Alexander V. Zybin, Kay Niemax, Yuri A. Kuritsyn, and Mikhail A. Bolshov "Double wavelength differential absorption as a technique for early diagnosis of breast cancer", Proc. SPIE 5973, Current Research on Laser Use in Oncology: 2000-2004, 597304 (7 December 2006); https://doi.org/10.1117/12.639949

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KEYWORDS

Absorption

Tissues

Semiconductor lasers

Scattering

Breast

Diagnostics

Photons

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