Polarization-sensitive optical coherence tomography for imaging of biological tissues

Xiaodong Chen; Yi Wang; Wanhui Li; Daoyin Yu

doi:10.1117/12.710956

27 October 2006 Polarization-sensitive optical coherence tomography for imaging of biological tissues

Xiaodong Chen, Yi Wang, Wanhui Li, Daoyin Yu

Proceedings Volume 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine; 60470T (2006) https://doi.org/10.1117/12.710956
Event: Fourth International Conference on Photonics and Imaging in Biology and Medicine, 2005, Tianjin, China

Abstract

Polarization sensitive optical coherence tomography (PS-OCT) is a new non-contact and non-invasive method for measuring the change of birefringence in biological tissues caused by pathological changes of body. It has great potential in imaging the structural properties of turbid biological media because the polarization state of light backscattered from biological tissues is influenced by the birefringence of fibrous structures. The arrangement is based on a Michelson interferometer with use of quarter-wave plates and polarimeter. Through the detection of light backscattered from biological tissues and reflected from a reference mirror, the optical phase delay between orthogonal polarization compositions propagating in the birefringence media can be measured. PS-OCT is a powerful tool for research of tendon, dentin, lesions, which have strong polarization effective. We in this paper describe the experimental scheme and its mathematical representation, along with the theory of PS-OCT imaging. Besides, we introduce a fiber-based PS-OCT system for measuring the tissue birefringence.

Citation Download Citation

Xiaodong Chen, Yi Wang, Wanhui Li, and Daoyin Yu "Polarization-sensitive optical coherence tomography for imaging of biological tissues", Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 60470T (27 October 2006); https://doi.org/10.1117/12.710956

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KEYWORDS

Polarization

Tissues

Optical coherence tomography

Birefringence

Beam splitters

Light sources

Sensors

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