Hemodynamic investigation on blood flow in a rugged microchannel

C. W. Park; G. M. Kim; S. H. Shin; S. J. Lee; Y. H. Ku; J. H. Jang

doi:10.1117/12.649749

5 December 2005 Hemodynamic investigation on blood flow in a rugged microchannel

C. W. Park, G. M. Kim, S. H. Shin, S. J. Lee, Y. H. Ku, J. H. Jang

Proceedings Volume 6050, Optomechatronic Micro/Nano Devices and Components; 60500Y (2005) https://doi.org/10.1117/12.649749
Event: Optomechatronic Technologies 2005, 2005, Sapporo, Japan

Abstract

The biological flow characteristics inside a rugged surface type microchannel are investigated experimentally using a micro-particle image velocimetry (micro-PIV) method. The main objectives of this study are to understand the blood flow structure inside a micro-domain blood vessel and to identify the feasibility of nano-scale fluorescent particles for velocity field measurement in a micron-sized channel. The flow field is analyzed with a spatial resolution of 1K×1K pixels at low Reynolds number flow. To obtain the spatial distributions of mean velocity, 100 instantaneous velocity fields are captured and ensemble-averaged. As a result, for the case of blood flow, there are substantial cell deformation and variations to pass through the rugged surface of a microchannel and the clear velocity vector field was acquired by using the present micro-PIV technique.

Citation Download Citation

C. W. Park, G. M. Kim, S. H. Shin, S. J. Lee, Y. H. Ku, and J. H. Jang "Hemodynamic investigation on blood flow in a rugged microchannel", Proc. SPIE 6050, Optomechatronic Micro/Nano Devices and Components, 60500Y (5 December 2005); https://doi.org/10.1117/12.649749

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KEYWORDS

Blood circulation

Blood

Velocity measurements

Particles

Microfluidics

CCD cameras

Visualization

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