Transmission profile function reconstruction for complex transmission interferometry: biomedical applications

Paulino Vacas-Jacques; Marija Strojnik; Gonzalo Paez

doi:10.1117/12.679547

7 September 2006 Transmission profile function reconstruction for complex transmission interferometry: biomedical applications

Paulino Vacas-Jacques, Marija Strojnik, Gonzalo Paez

Author Affiliations +

Proceedings Volume 6307, Unconventional Imaging II; 63070P (2006) https://doi.org/10.1117/12.679547
Event: SPIE Optics + Photonics, 2006, San Diego, California, United States

Abstract

We propose a novel method to reconstruct Transmission Profile Function (TPF) information based on visibility measurements. In specific occasions, V<<1, the TPF is proportional to the visibility squared. Extremely low visibilities (~10^-8) hinder the capacity of the technique to recover information. We evaluate three biomedical cases to confirm TPF reconstruction. First, we assess a three-dimensional multilayer skin model to demarcate limits on the reconstruction process. A three-dimensional female breast phantom with spherical tumors is evaluated next. We concentrate on technique performance to describe tissue morphology. Reconstructed TPFs with different resolutions are presented. Agreement between modeled and recovered information is demonstrated. Finally, a healthy and metastatic liver is compared. We demonstrate that a reconstructed TPF comparison enables (potentially) the diagnosis of alien tissue.

Citation Download Citation

Paulino Vacas-Jacques, Marija Strojnik, and Gonzalo Paez "Transmission profile function reconstruction for complex transmission interferometry: biomedical applications", Proc. SPIE 6307, Unconventional Imaging II, 63070P (7 September 2006); https://doi.org/10.1117/12.679547

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