Dual wavelength approach for the estimation of the relative concentration of two absorbers: Monte Carlo simulations

Angelo Sassaroli; Ning Liu; Sergio Fantini

doi:10.1117/12.698749

13 February 2007 Dual wavelength approach for the estimation of the relative concentration of two absorbers: Monte Carlo simulations

Angelo Sassaroli, Ning Liu, Sergio Fantini

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Proceedings Volume 6434, Optical Tomography and Spectroscopy of Tissue VII; 643412 (2007) https://doi.org/10.1117/12.698749
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

We describe a Monte Carlo test of a new method for the calculation of the relative concentrations of two localized absorbers in a highly scattering medium. The method, previously proposed by us, is based on a property of the intensity changes caused by the localized absorbers, which is strictly verified by diffusion theory within first order perturbation, and remains approximately verified beyond the limits of first order perturbation. The applicability of the method was theoretically and experimentally validated in an infinite medium geometry for "small size" perturbations, as well as for larger perturbations. The purpose of the Monte Carlo test reported here is to show that the method is applicable also to a slab geometry for a relatively large (both in size and optical contrast) perturbation. This test indicates that the dual wavelength approach to the estimation of the relative concentration of two absorbers can be insensitive to the medium geometry as well as the size and geometry of the localized inclusion.

Citation Download Citation

Angelo Sassaroli, Ning Liu, and Sergio Fantini "Dual wavelength approach for the estimation of the relative concentration of two absorbers: Monte Carlo simulations", Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 643412 (13 February 2007); https://doi.org/10.1117/12.698749

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KEYWORDS

Scattering

Monte Carlo methods

Photons

Tissues

Absorption

Mie scattering

Near infrared spectroscopy

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