High-resolution burn imaging in pig skin by photoacoustic microscopy

Hao F. Zhang; Konstantin Maslov; George Stoica; Lihong V. Wang

doi:10.1117/12.698005

13 February 2007 High-resolution burn imaging in pig skin by photoacoustic microscopy

Hao F. Zhang, Konstantin Maslov, George Stoica, Lihong V. Wang

Proceedings Volume 6437, Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; 64370A (2007) https://doi.org/10.1117/12.698005
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

Existing noninvasive imaging modalities fail to provide high-resolution depth-resolved imaging of skin burns in large depths. Hence, the measurement of burn depth, especially for partial-thickness burn, remains inaccurate. We used photoacoustic microscopy to measure the depth of acute thermal burns by imaging the microvasculature damage. In this work, partial-thickness burns were induced in vivo on pig skin. Limited by the flexibility of the photoacoustic scanning system, photoacoustic images of the burns were acquired after skin excision. Experimental results show that burn depth increases with longer heating duration. The maximum imaged burn depth measures ∼1.7 mm with a depth resolution of 15 &mgr;m.

Citation Download Citation

Hao F. Zhang, Konstantin Maslov, George Stoica, and Lihong V. Wang "High-resolution burn imaging in pig skin by photoacoustic microscopy", Proc. SPIE 6437, Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 64370A (13 February 2007); https://doi.org/10.1117/12.698005

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