Photothermal modulation of x-ray phase contrast images

Christopher M. Laperle; Guohua Cao; Theron J. Hamilton; Christoph Rose-Petruck; Gerald J. Diebold

doi:10.1117/12.729196

13 February 2007 Photothermal modulation of x-ray phase contrast images

Christopher M. Laperle, Guohua Cao, Theron J. Hamilton, Christoph Rose-Petruck, Gerald J. Diebold

Proceedings Volume 6437, Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; 64371N (2007) https://doi.org/10.1117/12.729196
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

The in-line x-ray phase-contrast imaging method relies on changes in index of refraction within a body to produce image contrast. In soft tissue, index of refraction variations arise from density changes so that phase contrast imaging provides a map of density gradients within a body. An intense, short pulse laser beam that is differentially absorbed by an object within a body will produce a thermal wave with an associated density change that propagates outwardly from the interface between the object and the body. Experiments are described where a pulsed Nd:YLF laser is synchronized to an image intensifier to record the effects of the energy deposited by a pulsed laser.

Citation Download Citation

Christopher M. Laperle, Guohua Cao, Theron J. Hamilton, Christoph Rose-Petruck, and Gerald J. Diebold "Photothermal modulation of x-ray phase contrast images", Proc. SPIE 6437, Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 64371N (13 February 2007); https://doi.org/10.1117/12.729196

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