Paper
1 May 2007 Study of a new parameter used in objective measurement of skin erythema
Keke Shang, Ying Liu, Yixing Lu, Yu Guo, Lijun Wang, Xiaoqi Chang
Author Affiliations +
Proceedings Volume 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine; 653413 (2007) https://doi.org/10.1117/12.741476
Event: Fifth International Conference on Photonics and Imaging in Biology and Medicine, 2006, Wuhan, China
Abstract
The objective measurement of skin erythema is of much importance in clinical dermatological diagnosis and new dermatological drug tests. The measurements that used currently are facing a main problem that all the measurements are deeply influenced by the melanin in the epidermis and the incident intensity. Basing on the skin optical model, a new parameter is introduced in order to describe the change of erythema. The new parameter is defined by the difference of the logarithm of the diffuse reflected light intensity between normal skin and erythema skin. The theoretical analysis shows that this new parameter can reflect directly the deviation of the concentration of haemoglobin from the normal range under the assumption of keeping the concentration of melanin constant and the illuminating light uniform. In addition, the experimental study also shows that this method is hardly influenced by the illuminating light intensity, and can be effectively applied in the clinical diagnosis.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Keke Shang, Ying Liu, Yixing Lu, Yu Guo, Lijun Wang, and Xiaoqi Chang "Study of a new parameter used in objective measurement of skin erythema", Proc. SPIE 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, 653413 (1 May 2007); https://doi.org/10.1117/12.741476
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KEYWORDS
Skin

Light

Light sources

Tissue optics

Absorption

Capillaries

Diffuse reflectance spectroscopy

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