Application of gold nanoparticles to x-ray diagnostics and photothermal therapy of cancer

G. S. Terentyuk; I. L. Maksimova; V. V. Tuchin; V. P. Zharov; B. N. Khlebtsov; V. A. Bogatyrev; L. A. Dykman; N. G. Khlebtsov

doi:10.1117/12.753446

22 June 2007 Application of gold nanoparticles to x-ray diagnostics and photothermal therapy of cancer

G. S. Terentyuk, I. L. Maksimova, V. V. Tuchin, V. P. Zharov, B. N. Khlebtsov, V. A. Bogatyrev, L. A. Dykman, N. G. Khlebtsov

Author Affiliations +

Proceedings Volume 6536, Saratov Fall Meeting 2006: Coherent Optics of Ordered and Random Media VII; 65360B (2007) https://doi.org/10.1117/12.753446
Event: Saratov Fall Meeting 2006, 2006, Saratov, Russian Federation

Abstract

We describe applications of colloidal gold nanoparticles and silica/gold nanoshells to photothermal therapy and X-ray diagnostics of cancer exemplified by spontaneous tumor of cats and dog. It is shown that the contrast of X-ray images of a cat mammalian tumor can be increased significantly by injection of 3-5-nm gold nanoparticles. We also present preliminary results of a complex approach to treatment a dog mouth cavity melanoma by using immunotherapy together with laser photothermolysis enhanced with silica/gold nanoshells.

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G. S. Terentyuk, I. L. Maksimova, V. V. Tuchin, V. P. Zharov, B. N. Khlebtsov, V. A. Bogatyrev, L. A. Dykman, and N. G. Khlebtsov "Application of gold nanoparticles to x-ray diagnostics and photothermal therapy of cancer", Proc. SPIE 6536, Saratov Fall Meeting 2006: Coherent Optics of Ordered and Random Media VII, 65360B (22 June 2007); https://doi.org/10.1117/12.753446

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