Paper
22 September 2007 Surface enhanced Raman spectroscopy on the tip of a plastic optical fiber
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Abstract
Surface Enhanced Raman Spectroscopy is a powerful analytical technique capable of single molecule detection sensitivity. We have detected SERS on the tip of a 3 mm-core diameter PMMA plastic optical fiber. The technique involves deposition of 30 nm gold nanoparticles followed by deposition of sample of interest to be analyzed. SERS enhancement has been demonstrated for several chemicals like glycerin and dye Rhodamine 6G as well biological molecules like Acetaminophen, aspirin and Streptavidin and poly-L-Lysine. It is shown that interfering spectrum of PMMA can be subtracted to reveal the SERS spectrum of molecule of interest. The technique can simplify SERS detection by connecting the other end of fiber directly to a spectrometer. SERS was recorded for various concentrations of analytes. Using a focused 633 nm laser, a detection sensitivity of 0.1picogram was established.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
J. M. Taguenang, A. Kassu, A. Sharma, and D. Diggs "Surface enhanced Raman spectroscopy on the tip of a plastic optical fiber", Proc. SPIE 6641, Plasmonics: Metallic Nanostructures and Their Optical Properties V, 66411X (22 September 2007); https://doi.org/10.1117/12.731246
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KEYWORDS
Gold

Polymethylmethacrylate

Surface enhanced Raman spectroscopy

Raman spectroscopy

Nanoparticles

Molecules

Silicon

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