Ultrasound-modulated optical tomography using four-wave mixing in photorefractive polymers

Huiliang Zhang; Philip Hemmer; Peng Wang; Shuji Rokutanda; Michiharu Yamamoto; Lihong V. Wang

doi:10.1117/12.764987

28 February 2008 Ultrasound-modulated optical tomography using four-wave mixing in photorefractive polymers

Huiliang Zhang, Philip Hemmer, Peng Wang, Shuji Rokutanda, Michiharu Yamamoto, Lihong V. Wang

Proceedings Volume 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; 68561S (2008) https://doi.org/10.1117/12.764987
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Ultrasound-modulated optical tomography uses a well focused ultrasound beam to modulate diffuse light inside soft biological tissues. This modality combines the advantages of ultrasound resolution with optical contrast. However, because of the low ultrasound modulation efficiency, the large background of un-modulated photons gives a low signal-to-noise ratio. Here we report a technique for detection of ultrasound-modulated light using a phase conjugated signal generated by four-wave mixing in a photorefractive polymer. The experimental results demonstrate the potential of this method to detect ultrasound-modulated optical signals in a highly scattering media with an excellent signal-to-noise ratio.

Citation Download Citation

Huiliang Zhang, Philip Hemmer, Peng Wang, Shuji Rokutanda, Michiharu Yamamoto, and Lihong V. Wang "Ultrasound-modulated optical tomography using four-wave mixing in photorefractive polymers", Proc. SPIE 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 68561S (28 February 2008); https://doi.org/10.1117/12.764987

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