A novel method of using hollow-core photonic crystal fiber as a Raman biosensor

Majid Naji; Altaf Khetani; Neil Lagali; Rejean Munger; Hanan Anis

doi:10.1117/12.763158

22 February 2008 A novel method of using hollow-core photonic crystal fiber as a Raman biosensor

Majid Naji, Altaf Khetani, Neil Lagali, Rejean Munger, Hanan Anis

Proceedings Volume 6865, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V; 68650E (2008) https://doi.org/10.1117/12.763158
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

A new method for using a non-selectively filled hollow-core photonic crystal fiber (HC-PCF) as a sensitive Raman spectroscopy platform suitable for biosensing applications is presented. A 1550 HC-PCF was completely filled with ethanol (core and cladding holes). Using a 785nm excitation laser, the Raman spectrum of ethanol in the fiber core was obtained and compared with the equivalent Raman spectrum of an ethanolfilled cuvette. Using a relatively short 9.5cm length of HC-PCF, a Raman signal enhancement factor of 40 over a bulk solution of ethanol was observed under the same excitation conditions. The small sample volume utilized and longer interaction length provides the potential for compact, sensitive, and low-power Raman sensing of biological materials

Citation Download Citation

Majid Naji, Altaf Khetani, Neil Lagali, Rejean Munger, and Hanan Anis "A novel method of using hollow-core photonic crystal fiber as a Raman biosensor", Proc. SPIE 6865, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V, 68650E (22 February 2008); https://doi.org/10.1117/12.763158

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