Diffuse optical tomography with time-gated perturbation Monte Carlo method

Jin Chen; Vivek Venugopal; Xavier Intes

doi:10.1117/12.822556

20 February 2009 Diffuse optical tomography with time-gated perturbation Monte Carlo method

Jin Chen, Vivek Venugopal, Xavier Intes

Proceedings Volume 7171, Multimodal Biomedical Imaging IV; 717113 (2009) https://doi.org/10.1117/12.822556
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Diffuse optical tomography using perturbation Monte Carlo method can overcome the drawback inherent to the classical model based on the diffusion equation for pre-clinical applications. The combined use of information from different time gates enables image reconstruction with accurate quantification and reducing the crosstalk between the absorption and the scattering coefficients. In this work, we apply this approach to solve an inverse problem of a 3D mouse model, and investigate the benefit to incorporate the time-resolved data into the optical reconstruction for quantitative functional imaging.

Citation Download Citation

Jin Chen, Vivek Venugopal, and Xavier Intes "Diffuse optical tomography with time-gated perturbation Monte Carlo method", Proc. SPIE 7171, Multimodal Biomedical Imaging IV, 717113 (20 February 2009); https://doi.org/10.1117/12.822556

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